The book Lifespan by David Sinclair explores the science of aging and potential interventions to extend human lifespan. The reviewer, with a background in biotech, finds the scientific parts compelling but critiques the lack of rigorous sources for some claims and the speculative nature of the later sections.
Lifespan by David Sinclair delves into the science of aging, presenting both current knowledge and future possibilities for extending human lifespan. The reviewer, who works in biotech, appreciates the scientific sections but is critical of the book's lack of detailed sources for some claims. The later parts of the book, which discuss societal implications and the need for more funding for anti-aging research, are seen as less groundbreaking for those already familiar with the topic. The reviewer also questions the credibility of some studies cited, particularly those with small sample sizes and marginal statistical significance. Overall, while the book is informative, it falls short in providing robust evidence for all its assertions.
Quick quotes
We are making progress every week in restoring the youthful epigenome of mice by delivering reprogramming factors. The pace of discovery is mind spinning. A full night of sleep for me and my lab members is increasingly rare.
If females and males are in the same environment, in general, females will live longer. It’s a common theme throughout the animal kingdom.
The future is bright due to early detection using genomics and biomarkers: